Astrologically speaking, 12th house in horoscope is the seat of loss and it includes sorrows, pains, and painful closures. The battle is half won when we know what to expect from the pains and gains. The 12th house in your horoscope is associated with the subconscious and hidden nature. It is the only bhava or house representing house loss, decline, isolation, and liberation and it is also known as Vyaya Bhava. According to some Vedic Astrologers, this house is also known for waste, expenses, misery, and knowledge. Some even consider it as the house of detachment. But when the 12th house is strong or in benefic influence, then the 12th house lord gives strong personality to the person.